Region 1A
#1 Florence vs. #8 Tiospa Zina
#4 Redfield vs. #5 Webster Area
#2 Sisseton vs. #7 Clark
#3 Groton Area vs. #6 Milbank
Region 2A
#1 Hamlin vs. #8 Flandreau Indian
#4 Sioux Valley vs. #5 Great Plains Lutheran
#2 Flandreau vs. #7 Elkton-Lake Benton
#3 Deubrook Area vs. #6 Deuel
Region 3A
#1 West Central vs. #8 Dell Rapids
#4 Tri-Valley vs. #5 McCook Central Montrose
#2 Sioux Falls Lutheran vs. #7 Baltic
#3 Garretson vs. #6 Madison
Region 4A
#1 Dakota Valley vs. #8 Parker
#4 Lennox vs. #5 Canton
#2 Vermillion vs. #7 Beresford
#3 Tea Area vs. #6 Elk Point-Jefferson
Region 5A
#4 Hanson vs. #5 Sanborn Central/Woonsocket
#2 Parkston vs. #7 Bon Homme
#3 Mount Vernon/Plankinton vs. #6 Andes Central/Dakota Christian
Region 6A
#1 Crow Creek vs. #8 McLaughlin
#4 Dupree vs. #5 Chamberlain
#2 Winner vs. #7 Stanley County
#3 Mobridge-Pollock vs. #6 Cheyenne-Eagle Butte
Region 7A
#4 Pine Ridge vs. #5 St. Francis Indian
#2 Red Cloud vs. #7 Little Wound
#3 Todd County vs. #6 Bennett County
Region 8A
#4 Hill City vs. #5 Custer
#2 Belle Fourche vs. #7 Lead-Deadwood
#3 Rapid City Christian vs. #6 Hot Springs
