| Lakota Tech vs. Lower Brule | 4:00 PM MT |
| Tiospaye Topa vs. McIntosh | 4:00 PM MT |
| White River vs. Belle Fourche | 5:30 PM CT |
| Langford Area vs. Oakes, ND | 6:00 PM CT |
| St. Francis Indian vs. Crazy Horse | 6:00 PM CT |
| Waubay/Summit vs. Clark/Willow Lake | 6:00 PM CT |
| Clark/Willow Lake vs. Waverly-South Shore | 6:00 PM CT |
| Elk Point-Jefferson vs. Canton | 6:30 PM CT |
| Faulkton Area vs. Wessington Springs | 6:30 PM CT |
| St. Thomas More vs. Campbell County, WY | 6:30 PM CT |
| Oldham-Ramona/Rutland vs. Lake Preston | 6:30 PM CT |
| Flandreau vs. Chester Area | 7:00 PM CT |
| O’Gorman vs. Brandon Valley | 7:00 PM CT |
| Sioux Falls Lincoln vs. Sioux Falls Washington | 7:00 PM CT |
| Rapid City Christian vs. Wall | 7:00 PM MT |
| Bennett County vs. Philip | 7:00 PM MT |
| Potter County vs. Aberdeen Christian | 7:15 PM CT |
| Madison vs. Dell Rapids | 7:30 PM CT |
| Chamberlain vs. Corsica-Stickney | 7:45 PM CT |
| Leola/Frederick Area vs. Northwestern | 8:00 PM CT |
